400

CHEM-40000 Advanced Inorganic Chemistry

Students study quantum chemistry, including the vector model of the atom; spectroscopic terms and states; transition metal complexes stereochemistry, spectral properties, magnetochemistry and reactions studied in the light of relevant bonding theories. The class also covers compounds of main group elements, with an emphasis on physical methods of investigation.

3

Prerequisites

CHEM 30000

CHEM-40100 Advanced Organic Chemistry

A study of physical organic chemistry, this course emphasizes reaction mechanisms, reaction kinetics, stereochemistry and physical principles.

3

Prerequisites

CHEM 23500 and CHEM 30500

CHEM-40200 Topics in Organic Chemistry

This course discusses of the current topics in organic chemistry.  Lab reports and/or research papers may be required.

3

Prerequisites

Consent of department chair may be required.

CHEM-40300 Nuclear Chemistry

Students explore the properties of atomic nuclei, including radioactivity and nuclear decay, nuclear reactions, penetration of a potential barrier by the alpha particle, Fermi's theory of beta decay, modern ideas of the structure of the nucleus, theories of low and intermediate energy-induced nuclear reactions, the deuteron problem and nucleon-nucleon scattering (See PHYS 41000).

3

Prerequisites

CHEM 30500

CHEM-40400 Radiochemistry

This course focuses on the nature, production and applications of radioactivity. Topics include radioactive decay processes, types of radioactive decay, atomic nuclei, interactions with matter and radiochemical instrumentation.

3

Prerequisites

CHEM 30500

CHEM-40500 Biochemistry 1

The focus of this course is on major classes of molecules found in the living cells: water, proteins, carbohydrates, lipids and nucleic acids. The course explores concepts of organic and physical chemistry as they apply to biological molecules. The organic functional groups that define the structures and determine the chemical and physical properties of the biomolecules and their building blocks are described. The concept of "structure determining the function" of biomolecules is explored. Emphasis is on the concepts of thermodynamics: entropy, enthalpy and the free energy as they apply to protein folding, ligand binding, the mechanism of enzyme catalysis and enzyme kinetics.

3

Prerequisites

CHEM 23500

Corequisites

CHEM 40600

CHEM-40600 Biochemistry 1 Lab

This is a laboratory course to accompany Biochemistry 1 lecture (CHEM 40500). This course introduces students to the methods used to design and run controlled experiments with proper standards. Experiments focus on techniques used in the purification and characterization of the different biological molecules mainly proteins, carbohydrates and lipids such as chromatography and spectroscopy. Experiments also focus on different aspects of enzyme methodology and enzyme kinetics.

1

Corequisites

CHEM 40500

CHEM-40700 Biochemistry 2

This course focuses mainly on bioenergetics and metabolism. Bioenergetics is the quantitative study of energy conversions in biological systems following the laws of thermodynamics. The focus is on the chemical reactions of the central metabolic pathways which are common to all forms of life. These pathways involve multienzymatic reactions that result in the degradation and synthesis of the different biological molecules at steady state conditions. The role of ATP and its production through glycolysis, citric acid cycle, Beta oxidation, urea cycle, oxidative deamination, transamination, electron transport and oxidative phosphorylation is explored in detail. The analysis of the control and integration of these pathways are also described. Emphasis is on energy coupling of reactions in biological systems and the thermodynamic properties of the reactions such as entropy (delta S), enthalpy (delta H) and free energy (delta G) and how they determine reaction spontaneity. The students will also be instructed in critical reading and analysis skills of original scientific, biochemical articles.

3

Prerequisites

CHEM 40500

CHEM-40800 Biochemistry 2 Lab

This is a laboratory course to accompany Biochemistry 2 lecture (CHEM 40700). New techniques are introduced. Students are expected to work independently in designing and preparing all reagents needed for the experiments. Experiments include the application of techniques such as chromatography, UV spectroscopy, immunoassays, electrophoresis, DNA fingerprinting, and NMR spectroscopy to analyze and characterize biological molecules. During the second half of the semester, students are expected to design and perform experiments for a research project.

1

Corequisites

CHEM 40700

CHEM-41500 Advanced Forensic Chemistry 1

This course includes detailed investigation of current topics in forensic chemistry and forensic science.   Topics include arson and explosives investigation, drug analysis, the analysis of paint and gunshot residue, and questioned documents analysis.   Students will also learn the basics of crime scene procedures, chain-of-custody, quality assurance, courtroom testimony, laboratory accreditation, and analyst certification. This course will include three hours of lecture per week along with a three hour weekly laboratory

4

Prerequisites

CHEM 23500

CHEM-41600 Advanced Forensic Chemistry 2

The second semester course will build on topics learned in Advanced Forensic Chemistry 1.   students will explore the principles of forensic identification analysis and comparison of biological evidentiary samples such as blood, semen, saliva, and other biological samples and tissues.   The course will include electrophoresis, DNA extraction procedures, polymerase chain reaction (PCR), DNA typing, sex and race determination, methods of DNA analysis and detection, and other topics.   This class will include three hours of lecture per week along with a three hour weekly laboratory.

4

Prerequisites

CHEM 41500

CHEM-41700 Trace Analysis

This course will provide a comprehensive and up-to-date overview of the field of trace analysis. Students will learn about sample acquisition and the analysis of trace organic pollutants using gas chromatography (GC) and gas chromatography mass spectrometry (GC-MS) techniques. These techniques will then be applied in the identification of unknown trace compounds. Statistical methods will be covered in the evaluation of experimental errors. This course will also cover governmental regulatory limits along with the methods for monitoring and enforcing these limits.

3

Prerequisites

CHEM 23500, CHEM 32000, and CHEM 33200

CHEM-41800 Advanced Toxicology

Students will explore the principles of toxicology, environmental problems, testing procedures, and governmental regulations. The toxicology and subsequent treatment of exposures to major drug categories, industrial chemicals, household consumer products, and drugs of abuse will be covered. The course will also cover the characterization and handling of physical evidence collected at the scene of a fire or explosion.

3

Prerequisites

CHEM 23500, CHEM 32000, and CHEM 33200

CHEM-42000 Advanced Chemical Laboratory Topics

This course may include any number of different advanced techniques for the synthesis, purification, and characterization of inorganic, organic, organometallic, or biochemical compounds.   Students may also study the synthesis and characterization of air-sensitive and water-sensitive organometallic compounds and transition metal complexes.   Complexes will be analyzed using a variety of instrumental methods.

2

Prerequisites

Consent of instructor and/or department chair.

CHEM-42100 Polymer Chemistry

This course explores mechanisms of polymerization reactions, the molecular weight distributions of products, the principles, limitations and advantages of the most important methods of molecular weight determination, the relationship of physical properties to structure and composition, the correlations of applications with chemical composition, and the applications of polymer chemistry to coatings.
3

Prerequisites

CHEM 22700

CHEM-42200 Colloidal and Surface Chemistry

This course explores the fundamentals of colloid interactions between surfaces, particles, and surfactants as well as the principles of self-assembly. Application of the principles of surface and colloidal chemistry to technologies involving particulate dispersions, emulsions, aerosols, wetting, flocculation, separation, and stabilization will also be discussed.
3

Prerequisites

CHEM 22700

CHEM-43000 Polarized Light Microscopy

The course covers principles, theory and practice of polarized light microscopy (PLM) useful for particle and materials characterization and identification. The identification of particles using the polarized light microscope has a variety of applications within the fields of biology and chemistry.
2

Corequisites

CHEM 43100

CHEM-43100 Polarized Light Microscopy Practicum

This course provides the practical experience to independently operate the polarized light microscope (PLM).
1

Corequisites

CHEM 43000

CHEM-43200 Raman Microspectroscopy

Raman Microspectroscopy is a powerful laboratory tool for analysis of unknowns using their spectrum, and has a variety of applications within the field of chemistry.
2

Corequisites

CHEM 43300

CHEM-43300 Raman Microspectroscopy Practicum

This course provides the practical experience to independently apply skills learned in Raman Microspectroscopy to unknown samples.
1

Corequisites

CHEM 43200

CHEM-43400 Microscopic Particle Handling

The modern laboratory has, as one of its principal investigative instruments, the microscope. Some materials require special handling and preparation prior to examination. This course covers particle isolation, manipulation and mounting in preparation for microscopic examination. These techniques permit the use of a variety of microscopes with applications within the fields of biology and chemistry.
2

Corequisites

CHEM 43500

CHEM-43500 Microscopic Particle Handling Practicum

This course provides the practical experience to independently prepare samples for their examination using a variety of microscopes.
1

Corequisites

CHEM 43400

CHEM-43600 Scanning Electron Microscopy

The modern laboratory has, as one of its principal investigative instruments, the scanning electron microscope. This course covers foundation, theory and use of scanning electron microscopes. The scanning electron microscope has a variety of applications within the fields of biology and chemistry.
2

Corequisites

CHEM 43700

CHEM-43700 Scanning Electron Microscopy Practicum

This course provides the practical experience to independently operate the scanning electron microscope (SEM).
1

Corequisites

CHEM 43600

CHEM-43800 Infrared Microscopy

The modern laboratory has, as one of its principal investigative instruments, the infrared microscope. The infrared microscope has a variety of applications within the fields of biology and chemistry.
2

Corequisites

CHEM 43900

CHEM-43900 Infrared Microscopy Practicum

This course provides the practical experience to independently operate the Infrared Microscope (FTIR).
1

Corequisites

CHEM 43800

CHEM-44000 Infrared Spectral Interpretation

The modern laboratory has, as one of its principal investigative tools, the analysis of unknowns using their spectrum. Spectral analysis has a variety of applications within the field of chemistry. The course explores techniques to determine unknown molecular structures from infrared spectra.
1

Corequisites

CHEM 44100

CHEM-44100 Infrared Spectral Interpretation Practicum

This course provides the practical experience to independently interpret spectral data from unknown samples.
1

Corequisites

CHEM 44000

CHEM-44200 White Powder Unknowns

The course utilizes microscopy and other methods to identify over 60 white powder samples.
2

Corequisites

CHEM 44300

CHEM-44300 White Powder Unknowns Practicum

The course provides the practical experience to independently identify unknown samples of over 60 white powders.
1

Corequisites

CHEM 44200

CHEM-44400 Digital Photomicrography

This course covers problem-solving techniques in capturing and documenting macroscropic and microscopic observations using scientifically acceptable methods.
2

Corequisites

CHEM 44500

CHEM-44500 Digital Photomicrography Practicum

This course covers problem-solving techniques in capturing and documenting macroscopic and microscopic observations using scientifically acceptable methods.
1

Corequisites

CHEM 44400

CHEM-44600 Introduction to Forensic Trace Evidence

The course covers problem-solving techniques in identifying crime scene trace evidence.
2

Corequisites

CHEM 44700

CHEM-44700 Introduction to Forensic Trace Evidence Practicum

The course provides the practical experience to independently identify crime scene trace evidence.
1

Corequisites

CHEM 44600

CHEM-44800 X-ray Microanalysis by Energy-Dispersive X-Ray Spectrometry

EDS is an analytical technique to determine the elemental or chemical characterization of unknown samples. This course covers those techniques with applications within the fields of biology and chemistry.
2

Corequisites

CHEM 44900

CHEM-44900 X-ray Microanalysis by Energy-Dispersive X-Ray Spectrometry Practicum

This course provides the practical experience to independently analyze samples for their elemental composition and chemical characterization. This course covers those techniques with applications within the fields of biology and chemistry.
1

Corequisites

CHEM 44800

CHEM-45000 Research

An opportunity for students to work with faculty members on problems at an advanced level. Lab reports and/or research papers may be required.

1-4

Prerequisites

Approval of instructor and/or chairperson.

CHEM-45100 Advanced Imaging Technique for the Scanning Electron Microscope

The modern laboratory has, as one of its principal investigative instruments, the scanning electron microscope. The scanning electron microscope has a variety of applications within the fields of biology and chemistry.
1

Corequisites

CHEM 45200

CHEM-45200 Advanced Imaging Techniques for the Scanning Electron Microscope Practicum

This course provides the practical experience to independently operate the scanning electron microscope (SEM) to achieve high quality images.
1

Corequisites

CHEM 45100

CHEM-45300 Forensic Fiber Identification

The Forensic Fiber Identification course offers techniques for the identification of natural and man-made fibers.
2

Corequisites

CHEM 45600

CHEM-45400 Gunshot Residue Identification

The course utilizes microscopy (SEM/EDS) to identify forensic samples of gunshot residue.
2

Corequisites

CHEM 45500

CHEM-45500 Gunshot Residue Identification

This course provides the practical experience to independently identify forensic samples of gunshot residues.
1

Corequisites

CHEM 45400

CHEM-45600 Forensic Fiber Identification Practicum

This course provides the practical experience to independently identify forensic samples of natural and man-made fibers.
1

Corequisites

CHEM 45300

CHEM-45700 Hair Comparison

The course offers techniques for the identification of animal and human hairs and introduction to the principles and practice of forensic hair comparison using microscopy and DNA analysis.
2

Corequisites

CHEM 45800

CHEM-45800 Hair Comparison Practicum

This course provides the practical experience to independently identify animal and human hair for forensic analyses.
1

Corequisites

CHEM 45700

CHEM-45900 Analysis of Low Explosives

The course covers the problem-solving techniques in identifying bomb scene evidence.
2

Corequisites

CHEM 46000

CHEM-46000 Analysis of Low Explosives Practicum

This course provides the practical experience to independently identify bomb scene evidence.
1

Corequisites

CHEM 45900

CHEM-46100 Pharmaceutical Contaminants

The course utilizes microscopy couples with sample isolation, preparation and analytical analysis of small particle contaminates.
2

Corequisites

CHEM 46200

CHEM-46200 Pharmaceutical Contaminants Practicum

This course provides the practical experience to independently interpret samples of contaminants from pharmaceutical products.
1

Corequisites

CHEM 46100

CHEM-46300 Pigment Identification

The course utilizes microscopy to identify paint materials for conservation professionals.
2

Corequisites

CHEM 46400

CHEM-46400 Pigment Identification Practicum

This course provides the practical experience to independently interpret samples of paints from artwork or architecture.
1

Corequisites

CHEM 46300

CHEM-46500 Capstone Project

In this course, students carry out a major project or set of topically-linked smaller projects from proposal through data collection and data analysis to dissemination. Capstone projects may be experimental, computational, or pedagogical depending on the students’ interests and emphasis within the major.  Students present their Capstone Project results in a written journal-style article, an oral presentation, and a poster.  This course partially fulfills the advanced writing requirement for the Chemistry/Biochemistry (Bachelor of Science) major.
1

Prerequisites

CHEM 39700

CHEM-47000 Internship

This course is designed to provide students with a supervised experience. A written report is required. Students wishing to enroll in this course should see the instructor. Approximately 70 clock hours are required for every semester hour credit.

1-6

Prerequisites

Approval of internship coordinator and chairperson.

CHEM-49700 Seminar

An opportunity for students to investigate a current topic in the chemical literature. The findings will be organized in a term paper and presented to the department.

1

Prerequisites

Approval of instructor and/or chairperson.

CHEM-49800 Special Topics

Subject matter of a specialized nature is covered in detail.  Lab reports and/or research papers may be required.

1-4

Prerequisites

Approval of instructor and/or chairperson.

CHEM-49900 Independent Study

Students undertake advanced study in Chemistry under the supervision of a departmental faculty member.

1-4

Prerequisites

Approval of instructor and/or chairperson. To qualify for an Independent Study, a student must have successfully completed 60 credit hours, at least 12 of which were earned at Lewis, and have earned at Lewis University a minimum 3.0 cumulative GPA.